We are a Leiden University based research platform of researchers who aim to understand the changing minds and brains of children and adolescents. We focus on healthy development, psychopathology, and the impact of adversity in social contexts. Our close collaboration brings high diversity in expertise and skill sets within CHANGE, strengthening and enriching our research questions, methods, and training opportunities for students. Our research includes methods of neuroimaging to investigate brain structure and function, computational modelling, sociometric analyses, hormone measures, and longitudinal approaches. Together, these diverse approaches form a more complete picture of the changes that take place during development. Transparency and open science are key to us, all our research materials can be accessed online. We frequently organize outreach events, as we value the societal impact of our work.

CHANGE platform is located at the developmental and educational psychology department at Leiden University. CHANGE members participates in the Leiden Institute for Brain and Cognition (LIBC), which is an interfaculty research network 

focusing on science valorisation and outreach, stimulating interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition based at Leiden University (see www.libc-leiden.nl or  libc-junior.nl for the LIBC junior hotspot).

The creation of CHANGE Leiden

Meet the people behind CHANGE

Anna Van Duijvenvoorde

Anna is an associate professor at CHANGE Leiden. She studies how brain development relates to adolescent’s decision-making and learning. 

Berna Güroglu

Berna is full professor of Neuroscience of Social Relations at CHANGE Leiden. She investigates social, emotional, and cognitive development from a neuroscience perspective.

Kiki Zanolie

Kiki is an assistant professor at CHANGE Leiden. She studies neurocognitive development and the role of social relations and social status on prosocial decision making, executive functions, and risk-taking in gifted and typically developing children and adolescents. 

Marieke Bos

Marieke is an assistant professor at CHANGE Leiden. She studies neurobiological mechanisms of the etiology of psychopathology in order to understand why mental health problems often emerge during adolescence. 

Jorien van Hoorn

Jorien is an assistant professor at CHANGE Leiden and a psychologist at De Bascule, academic center for child & adolescent psychiatry. She studies social and neurobiological development in adolescents with and without psychiatric disorders (e.g., ADHD and ASS). 

Lara Wierenga

Lara is an assistant professor at CHANGE Leiden and principal investigator on the Leiden Consortium of Individual Development. She is devoted to better understand genetic and environmental sex effects on brain development. Herewith she aims to better understand why some individuals are more susceptible to develop mental illness than others.

Ili Ma

Ili is an assistant professor at CHANGE Leiden (Leiden University). She is interested in the computational and neurocognitive processes that underlie learning and decision-making during adolescence. 

Lisa Schreuders

Lisa is an assistant professor at CHANGE Leiden. She studies how peer
relationships contribute to adolescents’ social and emotional well-being 
from a biopsychosocial perspective

Annelinde VandenBroucke

Annelinde is a senior project manager at CHANGE Leiden and program coordinator for the research performed within “NeuroLabNL Startimpuls”: a funding scheme from the Dutch Research Agenda (Nationale Wetenschapsagenda). 

Neeltje Blankenstein

Neeltje is an assistant professor at CHANGE Leiden. She examines the development of risk taking across several domains in typically-developing adolescents and adolescents with ADHD. 


Sanne Kellij

Sanne is a PhD student at CHANGE Leiden. She examines social-cognitive processes and underlying neurobiology of children, with a specific focus on persistently peer victimized children.

Nathalie van Kordelaar

Nathalie is a PhD student at CHANGE Leiden. She studies the role of puberty and individual differences on social and emotional development in gifted and typically developing children and adolescents.

Iris Koele

Iris is a PhD student at CHANGE Leiden. She studies the neural mechanisms of feedback processing in the context of peers in typically developing adolescents and adolescents with ADHD.

Selin Topel

Selin is a PhD candidate at the clinical psychology department at Leiden University and affiliated to CHANGE Leiden. She studies the relationship between resilience, uncertainty, and cognitive flexibility as part of the interdisciplinary Social Resilience and Security Program.

Kiki Zanolie

Vlog on perfectionism hosted by NeurolabNL Young. Kiki talks with Madelief about her experience with perfectionism  


Marieke Bos

Vlog on fear of failure hosted by NeurolabNL Young. Marieke talks with Renee about her experience with fear of failure and burn-out 


Marieke Bos & Lara Wierenga

(Un)gendered brains - a podcast where we reflect on how we study sex and gender differences in mental health in relation to the brain 


Lara Wierenga

Vlog presenting the public science book 'Atlas van ons brein' by Lara Wierenga and Dirma Janse, a graphical journey through neuroscience



Animation on learning from mistakes. Made in cooperation with Corpus and the Brain and Education Lab (English)


Animation on puberty and brain development . Made in cooperation with Corpus and the Brain and Education Lab (English)


Animation on learning and curiosity. Made in cooperation with Corpus and the Brain and Education Lab (English)

Marieke Bos

Corona dipje?  - NOS op 3 (Dutch Media) interviewed Marieke Bos for background information to create this VLOG about mental wellbeing during the corona pandemic (Dutch)

Marieke Bos

Chaos in het brein - On depression and aggresion during adolescence (Dutch)

Lisa Schreuders

- Wat vriendschap met je brein doet - On the role of friendship on the development of the brain (Dutch)

Anna van Duijvenvoorde

In or out? - On peer pressure and social exclusion during adolescence (Dutch)

Maaike Verburg & Christel Klootwijk

The CHANGE towards open science - On the necessity of research support towards open science (English)

Kiki Zanolie, and Marieke Bos  presented the NeurolabNL Young research agenda together with Eveline Crone and youth ambassadors to Marcel Levi, chair of the Dutch Research Council. The research agenda is led by Annelinde Vandenbroucke and is a collaboration between 8 universities, in which youth share what the want to learn about the brain. 

Mental health is just as important as physical health. That is one of the important lessons learned during the coronacrisis. Anna van Duijvenvoorde, Kiki Zanolie, Marieke Bos, Jorien van Hoorn, and Berna Güroglu contributed to a large collaboration of over 20 research institutes on mental wellbeing composed into a review report by the 'Nederlands Jeugdinstituut'

Annelinde Vandenbroucke developed a series of vodcasts for, with and by adolescents with NeurolabNL Young in collaboration with experts Kiki Zanolie, Marieke Bos, Lucres Nauta-Jansen and Thimo van der Pol (in Dutch; also available as podcast)

Jorien van Hoorn explains in 'Rachel valt Binnen', a Dutch educational television program, about peer pressure. Click here to see the episode (in Dutch; see at 15 min 45 sec).

Lara Wierenga  published a public science book ‘Atlas van ons Brein’, a graphical journey through neuroscience in collaboration with graphical designer Dirma Janse. An interpretation and translation of research using insightful infographics. In this book I answer everything you wanted to know about your brain. 

Lara Wierenga tells on national television about the importance of the opportunities created by the Dutch government for young researchers [NOS journaal in Dutch; see at 9 min 54 sec]

Berna Güroglu and Anna van Duijvenvoorde as part of the Growing Up Together in Society (GUTS) consortium, led by Eveline Crone, received a gravitation grant.  Berna tells about the aims of the consortium. 

Marieke Bos received a Grass Shoots grant from the Faculty of Social Sciences to develop interactive video material to train student's clinical skills. 

Marieke Bos received a YAL Outreach grant in collaboration with Lara Wierenga. With this grant they will develop a podcast which will be made for their Lorentz Workshop on ‘Rethinking sex differences in neuroscience of mental health’ 

CHANGE participated at Expeditie Next, a huge national science fair for children. We developed the brain game with true or false fun facts about the brain to debunk brain myths, in collaboration with Brain and Education Lab members.

Lara Wierenga and Marieke Bos received a grant to organize a Lorentz Center Workshop on “Rethinking sex in neuroscience of mental health”. They also received a Leiden University Fund grant enabling them to host a youth panel connected to the workshop.  

Samenweten, initiative from KNAW and NWO, talks with  Annelinde Vandenbroucke in a new blogpost about science communication activities of CHANGE members in collaboration with Brain and Education Lab members.  [Dutch]

Berna Güroğlu explains in 'Klokhuis' what happens in the brain when you see your friends. Klokhuis is an educational television program for youth on Dutch television. Click here to see the episode (in Dutch).

Science communication: appreciated and acknowledged!  

Annelinde Vandenbroucke, Neeltje van den Bedem, Berna Güroğlu, Iris Koele, and Kiki Zanolie, received an award by the Royal Netherlands Academy of Arts and Sciences to continue their work in science communication. Together with Dietsje Jolles and Linda van Leijenhorst (Brain and Education Lab), they will develop new science communication products together with adolescents. 

Kiki Zanolie is selected to tweet for @NL_Wetenschap,  a twitter account in which every week a different Dutch scientist tells about their science and lives as a scientist. Keep an eye out in the summer of 2022.

Annelinde Vandenbroucke, Marieke Bos, Anna van Duijvenvoorde, and Berna Güroğlu, together with the project leaders of NeurolabNL Startimpuls 

received a science communication grant for NeurolabNL Young. In this project young people will design social media communication products to to inform peers about scientific findings on adolescence. 

Youth, brain science and law: new directions for research and practice. Anna van Duijvenvoorde organizes a webinar on February 18th discussing societal relevant issues regarding youth and law. For more information, or to register click here.

Berna Güroglu published in Nature Communications together with Elisabeth Schreuders, Barbara Braams and Eveline Crone. They found that friendship stability is associated with ventral striatum response in vicarious rewards.

Susanne Asscheman, Kiki Zanolie, and Marieke Bos investigated well-being of adolescents during the COVID-19 pandemic. "Mood variability among early adolescents in times of social constraints: A daily diary study during the COVID-19 pandemic" is now available as pre-print

The e-book of Frontiers for Young Minds special issue is out! CHANGE members Anna van Duijvenvoorde, Bianca Westhoff, and Iris Koele contributed to this outreach initiative as authors of two articles, while Sabine Peters was one of the editors. We are proud of this amazing issue!

Boys have a less favorable academic career and girls a less favorable job career, but his is not due to differences in the brain or skills as reported by the Dutch Educational Council for which Lara Wierenga and Eveline Crone (SYNC Lab) performed literature research. Click here for the report (Dutch).

We are very proud of CHANGE Leiden member Anna van Duijvenvoorde for winning the prestigious Heineken Young Scientist Award for her research on the development of the brain and behaviour in adolescents. Congratulations Anna! 

CHANGE members Bianca Westhoff and Iris Koele, together with Ilse van de Groep (SYNC lab) reached a young audience explaining their research in Frontiers for Young Minds, an outreach initiative involving reviews by children and adolescents

You can find us on Tiwitter: @Leiden_CHANGE
Also, many of our CHANGE Leiden members are on Twitter; see our personal pages for our Twitter accounts


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